Content：3. What are major categories of an “artificial liver”?
Generally speaking, there are three types of artificial liver as follows:
1) Non-biological artificial liver: a series of devices used for
eliminating toxin in human body, including hemodialysis, hemofiltration, hemoperfusion and hemotranspostion. The last function could also supply biological activating substances to the human body, thus being called the “transitional artificial liver”
2) Biological artificial liver: the extracorporeal device consisted of a human liver of the same or different types, liver tissue pieces, cultured liver cells, liver cell particulates, liver cell enzyme and other biosynthetic materials, including three parts: isolated hepatic perfusion，human-mammal intercross circulation, extracorporeal bioreactor (containing liver enzyme, liver cell content, liver tissue pieces and cultured liver cells, etc). Since the 90’s of the 20th century, biological artificial liver specially refers to the c[]
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Content：2. Who are suitable liver disease patients for an “artificial liver”?(By Jin Rui, a professor from Beijing YouAn Hospital;
Quoting from Expert Consulation Center for Liver Disease of Health Online)
A: The primary function of an “artificial liver” is to partly eliminate those toxic substances more than molecular weight in a patient’s body, such as endotoxin, bilirubin, cholic acid, tumor necrotic factors, complement activating substances, and alleviate liver inflammation. Meanwhile, the transpositional fresh blood of the same type as the patient’s provides some biological activating substances, such as plasma protein, cruor factors as well as opsonin, which would not only alleviate oedema and bleeding of the patient but also reduce the possibility of being infected and make it favorable for the recuperation and regeneration of liver cell. The clinical trials without and with an “artificial liver” showed the drastic decrease of serum bilirubin and hepatic coma. Therefore, it[]
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Content：1. What is an artificial liver?
(By Jin Rui, a professor from Beijing YouAn Hospital;
Quoting from Expert Consulation Center for Liver Disease of Health Online)
Answer (“A”): Various types of liver disease, such as viral hepatitis, drug hepatitis, alcoholic hepatitis, toxic liver failure, metabolic hepatitis and liver cancer, would give rise to abnormal liver function. When the liver disorder becomes so severe that the human liver is not available for normal metabolic need, the patient would otherwise suffer from a series of clinical symptoms like hepatic coma or malignant jaundice, which are summarized as liver failure medically. In this stage, the great part of the patient’s liver has denatured or become necrotic, resulting in sever metabolic disorder and accumulation of noxious substances in the human body. Hardly any treatment or operation would perform effective to save the patient, leading to high mortality rate. In response to t[]
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